IEDB Analysis Resource
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MHC-II Binding Predictions
Specify Sequence(s)
Enter protein sequence(s) in FASTA format
Or select file containing sequence(s)
Choose a Prediction Method
Prediction Method
Show all the method versions:
NetMHCIIpan 4.1 EL (recommended epitope predictor-2023.09)
NetMHCIIpan 4.1 BA (recommended binding predictor-2023.09)
IEDB recommended 2.22
IEDB recommended 2.18
NetMHCIIpan 4.3 EL
NetMHCIIpan 4.3 BA
NetMHCIIpan 4.2 EL
NetMHCIIpan 4.2 BA
NetMHCIIpan 4.0 EL
NetMHCIIpan 4.0 BA
NetMHCIIpan 3.2
NetMHCIIpan 3.1
Consensus 2.22
Consensus 2.18
NN-align 2.3 (NetMHCII 2.3)
NN-align 2.2 (NetMHCII 2.2)
SMM-align (NetMHCII 1.1)
Combinatorial library
Sturniolo
Help on prediction method selections
Specify what to make binding predictions for
Select species/locus
Select MHC allele(s)
Select α & β chains separately if applicable:
Select full HLA reference set
:
Select 7-allele HLA reference set:
Allele
Upload allele file
Select length(s)
default
12-18
as is
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
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Specify Output
Sort peptides by
Position in sequence
Adjusted Rank
Output format
XHTML table
Text file
Email address (optional)