Automated Server Benchmarks

MHCI Weekly Benchmark results

Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.

Server	Overall	SRCC	AUC
ANN 3.4	-	-	-
ANN 4.0	73	72	75
ARB	48	44	51
IEDB Consensus	53	49	58
NetMHCcons	-	-	-
NetMHCpan 2.8	-	-	-
NetMHCpan 3.0	-	-	-
NetMHCpan 4.0 BA	78	79	77
NetMHCpan 4.0 EL	37	37	37
NetMHCpan 4.1 BA	74	75	73
NetMHCpan 4.1 EL	18	18	18
PickPocket	53	53	53
SMM	61	60	62
SMMPMBEC	40	41	39
mhcflurry 1.2.0	75	74	75

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB Reference	Allele	Peptide Length	Peptide Count	Positive Count	Measurement type	ANN 3.4		ANN 4.0		ARB		IEDB Consensus		NetMHCcons		NetMHCpan 2.8		NetMHCpan 3.0		NetMHCpan 4.0 BA		NetMHCpan 4.0 EL		NetMHCpan 4.1 BA		NetMHCpan 4.1 EL		PickPocket		SMM		SMMPMBEC		mhcflurry 1.2.0
IEDB Reference	Allele	Peptide Length	Peptide Count	Positive Count	Measurement type	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC	SRCC	AUC
1047688	HLA-A*01:01	9	31	3	binary	-	-	0.500	0.988	0.488	0.976	0.494	0.982	-	-	-	-	-	-	0.476	0.964	0.427	0.917	0.476	0.964	0.354	0.845	0.470	0.958	0.488	0.976	0.476	0.964	0.488	0.976
1047688	HLA-A*01:01	10	10	2	binary	-	-	0.609	0.938	0.522	0.875	0.567	0.906	-	-	-	-	-	-	0.609	0.938	0.522	0.875	0.609	0.938	0.522	0.875	0.701	1.000	0.655	0.969	0.522	0.875	0.609	0.938
1047688	HLA-A*02:01	9	31	6	binary	-	-	0.566	0.913	0.434	0.883	0.434	0.887	-	-	-	-	-	-	0.475	0.847	0.310	0.727	0.493	0.860	-0.064	0.453	0.545	0.900	-	-	0.438	0.820	0.429	0.813
1047688	HLA-A*03:01	9	31	2	binary	-	-	0.000	0.500	-0.191	0.276	-0.073	0.414	-	-	-	-	-	-	-0.117	0.362	-0.308	0.138	-0.044	0.448	-0.294	0.155	-0.279	0.172	-0.132	0.345	-0.147	0.328	-0.250	0.207
1047688	HLA-A*29:02	9	31	7	binary	-	-	0.060	0.542	0.052	0.536	0.026	0.518	-	-	-	-	-	-	0.129	0.589	0.000	0.500	0.078	0.554	-0.224	0.345	0.112	0.577	0.035	0.524	0.026	0.518	0.052	0.536
1047688	HLA-A*29:02	10	10	4	binary	-	-	-0.142	0.417	-0.142	0.417	-0.284	0.333	-	-	-	-	-	-	-0.142	0.417	0.071	0.542	-0.071	0.458	0.000	0.500	0.000	0.500	-0.284	0.333	-0.355	0.292	-0.071	0.458
1047688	HLA-B*07:02	9	31	2	binary	-	-	0.382	0.948	0.396	0.966	0.382	0.948	-	-	-	-	-	-	0.396	0.966	0.264	0.810	0.396	0.966	0.264	0.810	0.401	0.966	0.382	0.948	0.382	0.948	0.396	0.966
1047688	HLA-B*15:01	9	31	3	binary	-	-	0.232	0.726	0.171	0.667	0.171	0.667	-	-	-	-	-	-	0.244	0.738	0.232	0.726	0.207	0.702	0.134	0.631	0.049	0.548	0.183	0.679	0.183	0.679	0.220	0.714
1047688	HLA-B*15:01	10	10	2	binary	-	-	0.174	0.625	-	-	0.000	0.500	-	-	-	-	-	-	0.000	0.500	0.174	0.625	0.000	0.500	0.174	0.625	-0.174	0.375	0.000	0.500	0.000	0.500	0.000	0.500
1047688	HLA-B*35:01	9	31	6	binary	-	-	0.447	0.827	0.110	0.580	0.507	0.873	-	-	-	-	-	-	0.612	0.947	0.593	0.933	0.612	0.947	0.511	0.873	0.361	0.763	0.493	0.860	0.425	0.810	0.630	0.960
1047688	HLA-C*07:01	9	31	8	binary	-	-	0.041	0.527	-	-	0.099	0.565	-	-	-	-	-	-	0.140	0.592	0.025	0.516	0.124	0.582	0.025	0.516	0.087	0.571	0.037	0.524	0.025	0.516	-	-