IEDB Analysis Resource

MHCII Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
Comblib matrices 5 0 9
Consensus IEDB method 5 9 0
NN-align 73 73 73
NN-align 2.3 50 18 82
NetMHCIIpan-3.1 32 27 36
NetMHCIIpan-3.2 59 55 64
NetMHCIIpan-4.0 BA 50 46 55
NetMHCIIpan-4.0 EL 77 64 91
NetMHCIIpan-4.1 BA 41 36 46
NetMHCIIpan-4.1 EL 91 82 100
SMM-align 55 91 18
Tepitope (Sturniolo) 64 100 27

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Count
Positive
Count
Measurement
type
Comblib matrices Consensus IEDB method NN-align NN-align 2.3 NetMHCIIpan-3.1 NetMHCIIpan-3.2 NetMHCIIpan-4.0 BA NetMHCIIpan-4.0 EL NetMHCIIpan-4.1 BA NetMHCIIpan-4.1 EL SMM-align Tepitope (Sturniolo)
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1042786   HLA-DRB1*01:01   26   4   ic50   0.100   0.614   0.236   0.591   0.475   0.727   0.245   0.727   0.331   0.659   0.433   0.716   0.422   0.705   0.453   0.886   0.408   0.693   0.479   0.909   0.480   0.636   0.500   0.648