IEDB Analysis Resource

MHCII Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
NN-align 44 38 50
NetMHCIIpan-3.1 49 52 47
Comblib matrices 12 20 4
SMM-align 78 73 83
Tepitope (Sturniolo) 38 37 40
Consensus IEDB method 61 62 59

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Count
Positive
Count
Measurement
type
NN-align NetMHCIIpan-3.1 Comblib matrices SMM-align Tepitope (Sturniolo) Consensus IEDB method
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1038237   HLA-DRB1*01:01   18   3   ic50   0.350   0.756   0.401   0.800   -0.011   0.633   0.463   0.867   0.588   0.867   0.382   0.811 
 1038237   HLA-DRB1*04:01   18   8   ic50   0.245   0.713   0.197   0.625   -   -   0.358   0.725   0.293   0.738   0.366   0.762 
 1038237   HLA-DRB1*04:05   18   6   ic50   0.587   0.778   0.509   0.764   -   -   0.643   0.861   0.311   0.736   0.595   0.819 
 1038237   HLA-DRB1*07:01   18   6   ic50   0.534   0.889   0.655   0.889   0.750   0.861   0.680   0.903   0.541   0.875   0.649   0.854 
 1038237   HLA-DRB1*08:02   18   2   ic50   0.238   0.875   0.366   0.969   -   -   0.278   0.938   0.211   0.906   0.300   0.922 
 1038237   HLA-DRB1*09:01   18   4   ic50   0.581   1.000   0.534   0.964   -0.367   0.384   0.461   0.964   -   -   0.540   0.946 
 1038237   HLA-DRB1*15:01   18   8   ic50   0.461   0.812   0.470   0.825   -   -   0.738   0.900   0.551   0.800   0.700   0.887 
 1038237   HLA-DRB3*01:01   18   3   ic50   0.755   0.956   0.834   0.889   -0.024   0.578   0.888   1.000   -   -   0.789   0.989 
 1038237   HLA-DRB4*01:01   18   4   ic50   0.574   0.964   0.555   0.857   0.246   0.804   0.539   0.875   -   -   0.465   0.929