IEDB Analysis Resource

MHCII Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
NN-align 54 54 54
NetMHCIIpan-3.1 - - -
Comblib matrices 13 13 13
SMM-align 52 52 52
Tepitope (Sturniolo) 27 27 27
Consensus IEDB method 85 85 85

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Count
Positive
Count
Measurement
type
NN-align NetMHCIIpan-3.1 Comblib matrices SMM-align Tepitope (Sturniolo) Consensus IEDB method
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1037883   HLA-DRB1*01:01   62   34   binary   0.503   0.792   -   -   0.302   0.678   0.251   0.646   0.364   0.713   0.396   0.733 
 1037883   HLA-DRB1*04:01   62   32   binary   0.422   0.744   -   -   -   -   0.514   0.797   0.426   0.748   0.501   0.789 
 1037883   HLA-DRB1*07:01   62   27   binary   0.606   0.853   -   -   0.414   0.741   0.637   0.871   0.536   0.815   0.678   0.895 
 1037883   HLA-DRB1*15:01   62   22   binary   0.590   0.856   -   -   -   -   0.501   0.802   0.408   0.753   0.590   0.868