IEDB Analysis Resource

MHCII Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
NN-align 60 60 60
NetMHCIIpan-3.1 0 0 0
Comblib matrices 90 100 80
SMM-align 30 40 20
Tepitope (Sturniolo) 30 20 40
Consensus IEDB method 90 80 100

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Count
Positive
Count
Measurement
type
NN-align NetMHCIIpan-3.1 Comblib matrices SMM-align Tepitope (Sturniolo) Consensus IEDB method
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1036884   HLA-DRB1*01:01   65   2   binary   -0.014   0.476   -0.005   0.492   -0.123   0.294   -0.024   0.460   0.005   0.647   -0.090   0.349 
 1036884   HLA-DRB1*04:01   65   9   binary   -0.078   0.435   -0.038   0.468   -   -   -0.040   0.466   -0.076   0.467   -0.066   0.474 
 1036884   HLA-DRB1*04:02   65   3   binary   -   -   -0.039   0.446   -   -   -   -   0.006   0.548   -0.004   0.540 
 1036884   HLA-DRB1*04:04   65   6   binary   0.071   0.571   -0.051   0.449   -   -   -0.008   0.492   0.098   0.624   0.067   0.606 
 1036884   HLA-DRB1*07:01   65   3   binary   0.113   0.656   -0.055   0.425   0.143   0.726   0.039   0.554   0.016   0.618   0.113   0.763