IEDB Analysis Resource

MHCII Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NN-align 69 68 69
NetMHCIIpan-3.1 75 79 70
Comblib matrices 0 0 0
SMM-align 26 26 26
Tepitope (Sturniolo) 52 49 54
Consensus IEDB method 60 55 64

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

IEDB
Reference
Allele Peptide
Count
Positive
Count
Measurement
type
NN-align NetMHCIIpan-3.1 Comblib matrices SMM-align Tepitope (Sturniolo) Consensus IEDB method
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1031406   H2-IAb   24   16   ic50   0.780   0.992   0.902   0.984   -   -   0.692   0.969   -   -   0.752   0.992 
 1031683   HLA-DRB1*01:01   17   12   binary   0.738   0.967   0.764   0.983   0.105   0.567   0.580   0.867   0.567   0.858   0.606   0.883 
 1031683   HLA-DRB1*04:01   16   6   binary   0.196   0.617   0.196   0.617   -   -   0.028   0.517   0.421   0.750   0.056   0.533 
 1031683   HLA-DRB1*07:01   17   9   binary   0.818   0.972   0.818   0.972   0.253   0.646   0.746   0.931   0.867   1.000   0.770   0.944 
 1031683   HLA-DRB1*09:01   17   13   binary   0.651   0.942   0.736   1.000   0.144   0.596   0.368   0.750   -   -   0.396   0.769 
 1031683   HLA-DRB1*11:01   16   11   binary   0.483   0.800   0.307   0.691   -   -   0.570   0.855   0.470   0.818   0.572   0.855 
 1031683   HLA-DRB1*15:01   17   13   binary   0.340   0.731   0.481   0.827   -   -   0.283   0.692   0.241   0.663   0.425   0.788