IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
NetMHCpan 2.8 35 37 34
NetMHCpan 3.0 30 30 31
NetMHCpan 4.0 46 56 37
SMM 78 73 83
ANN 3.4 52 50 54
ANN 4.0 40 41 40
ARB 21 5 38
SMMPMBEC 84 80 87
IEDB Consensus 64 67 60
NetMHCcons 48 50 47
PickPocket 35 33 36
mhcflurry 1.2.0 86 91 82
DeepSeqPa - - -
MultiPan - - -

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0 DeepSeqPa MultiPan
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1037887   H-2-Kd   8   22   2   ic50   0.469   0.575   0.569   0.650   -   -   0.617   0.575   0.481   0.550   0.412   0.625   -   -   0.565   0.575   0.542   0.575   0.471   0.550   0.413   0.600   0.596   0.675   -   -   -   - 
 1037887   H-2-Kd   9   38   16   ic50   0.827   0.977   0.793   0.952   0.820   0.966   0.791   0.969   0.778   0.946   0.792   0.972   0.727   0.960   0.798   0.969   0.797   0.967   0.797   0.960   0.817   0.980   -   -   -   -   -   - 
 1037887   H-2-Kd   10   34   11   ic50   0.150   0.439   0.288   0.518   0.326   0.538   0.579   0.708   0.454   0.609   0.299   0.502   0.155   0.549   0.575   0.700   0.412   0.573   0.362   0.561   0.209   0.470   0.579   0.664   -   -   -   - 
 1037887   H-2-Kd   11   38   11   ic50   0.557   0.778   0.614   0.815   0.627   0.811   0.790   0.832   0.706   0.835   0.661   0.791   -   -   0.788   0.842   0.770   0.828   0.648   0.815   0.539   0.774   -   -   -   -   -   -