IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.


Server Overall SRCC AUC
NetMHCpan 2.8 78 86 71
NetMHCpan 3.0 54 50 58
NetMHCpan 4.0 62 42 82
SMM 32 36 28
ANN 3.4 64 64 64
ANN 4.0 42 54 31
ARB 57 38 76
SMMPMBEC 42 57 28
IEDB Consensus 54 67 42
NetMHCcons 69 68 71
PickPocket 2 4 0
mhcflurry 1.2.0 100 100 100
DeepSeqPa 63 25 100

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here.

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0 DeepSeqPa
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1037895   HLA-A*02:01   9   12   8   ic50   0.692   0.719   0.497   0.656   0.587   0.719   0.657   0.688   0.692   0.750   0.643   0.656   0.643   0.719   0.699   0.688   0.677   0.703   0.664   0.719   0.503   0.562   0.790   0.781   0.636   0.781 
 1037895   HLA-A*02:01   10   11   6   ic50   0.691   0.733   0.700   0.833   0.573   0.767   0.355   0.567   0.555   0.700   0.573   0.700   0.536   0.767   0.355   0.567   -   -   0.636   0.733   0.296   0.550   -   -   -   -