IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NetMHCpan 2.8 44 45 42
NetMHCpan 3.0 62 61 64
NetMHCpan 4.0 76 76 76
SMM 50 45 55
ANN 3.4 47 49 45
ANN 4.0 89 91 88
ARB 24 15 33
SMMPMBEC 39 33 45
IEDB Consensus 67 58 76
NetMHCcons 48 30 67
PickPocket 35 36 33
mhcflurry 1.2.0 61 61 61

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1031072   HLA-A*02:01   9   28   23   ic50   0.802   0.983   0.852   0.991   0.875   1.000   0.862   0.991   0.841   0.983   0.887   1.000   0.847   1.000   0.861   0.991   0.828   0.991   0.837   0.991   0.799   0.974   0.888   1.000 
 1031072   HLA-A*02:01   10   16   13   ic50   0.850   0.949   0.835   0.923   0.879   0.949   0.718   0.872   0.756   0.872   0.841   0.923   0.609   0.692   0.709   0.872   0.805   0.872   0.771   0.872   0.712   0.821   0.691   0.821 
 1033576   HLA-A*02:01   9   191   13   binary   0.112   0.628   0.116   0.633   0.113   0.630   0.112   0.632   0.121   0.638   0.147   0.668   0.063   0.573   0.110   0.626   0.130   0.678   0.109   0.652   0.125   0.670   0.123   0.641