IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NetMHCpan 2.8 45 45 45
NetMHCpan 3.0 77 77 77
NetMHCpan 4.0 80 77 82
SMM 25 23 27
ANN 3.4 61 45 77
ANN 4.0 93 100 86
ARB 2 5 0
SMMPMBEC 30 27 32
IEDB Consensus 61 77 45
NetMHCcons 57 50 64
PickPocket 7 5 9
mhcflurry 1.2.0 68 68 68

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1033071   HLA-A*02:01   9   113   41   ic50   0.809   0.873   0.816   0.876   0.812   0.876   0.802   0.866   0.803   0.873   0.822   0.876   0.787   0.850   0.804   0.866   0.809   0.868   0.808   0.874   0.776   0.852   0.821   0.872 
 1033071   HLA-A*02:01   10   77   12   ic50   0.833   0.881   0.856   0.891   0.857   0.899   0.832   0.881   0.848   0.915   0.866   0.896   0.801   0.856   0.831   0.883   0.858   0.888   0.838   0.888   0.826   0.878   0.834   0.901