IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NetMHCpan 2.8 81 80 82
NetMHCpan 3.0 74 75 73
NetMHCpan 4.0 65 64 66
SMM 34 34 34
ANN 3.4 78 75 82
ANN 4.0 41 41 41
ARB 13 14 11
SMMPMBEC 52 52 52
IEDB Consensus 30 30 30
NetMHCcons 82 80 84
PickPocket 40 39 41
mhcflurry 1.2.0 38 36 39

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1031959   HLA-B*27:05   8   97   30   binary   -0.017   0.490   -0.022   0.486   -0.020   0.488   -0.068   0.458   -0.056   0.465   -0.035   0.478   -0.041   0.476   -0.064   0.460   -0.076   0.457   -0.041   0.479   -0.023   0.487   -0.077   0.452 
 1031959   HLA-B*27:05   9   13457   9396   binary   0.161   0.601   0.180   0.613   0.158   0.599   0.161   0.601   0.163   0.602   0.161   0.601   0.145   0.591   0.159   0.600   0.153   0.596   0.162   0.602   0.151   0.595   0.153   0.596 
 1031959   HLA-B*27:05   10   7565   5499   binary   0.188   0.622   0.190   0.623   0.190   0.623   0.187   0.621   0.196   0.627   0.181   0.617   0.142   0.592   0.197   0.627   0.189   0.622   0.192   0.625   0.172   0.611   0.188   0.622 
 1031959   HLA-B*27:05   11   5330   3999   binary   0.230   0.653   0.223   0.648   0.224   0.649   0.212   0.641   0.229   0.653   0.211   0.641   0.179   0.620   0.217   0.645   0.216   0.644   0.230   0.653   0.227   0.649   0.228   0.652