IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NetMHCpan 2.8 70 67 73
NetMHCpan 3.0 65 58 73
NetMHCpan 4.0 70 73 67
SMM 35 15 55
ANN 3.4 59 49 70
ANN 4.0 89 82 97
ARB 26 9 42
SMMPMBEC 49 39 58
IEDB Consensus 61 55 67
NetMHCcons 74 76 73
PickPocket 47 18 76
mhcflurry 1.2.0 89 79 100

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1031253   HLA-A*03:01   9   14   9   ic50   0.780   0.933   0.767   0.933   0.798   0.956   0.692   0.867   0.727   0.889   0.793   0.956   0.473   0.711   0.754   0.911   0.730   0.900   0.758   0.911   0.710   0.956   0.833   0.956 
 1031253   HLA-B*07:02   9   13   7   ic50   0.966   1.000   0.966   1.000   0.977   1.000   0.960   1.000   0.960   1.000   0.977   1.000   0.889   1.000   0.971   1.000   0.974   1.000   0.974   1.000   0.875   1.000   0.960   1.000 
 1031253   HLA-B*27:05   9   12   7   ic50   0.592   0.629   0.567   0.629   0.480   0.571   0.445   0.629   0.595   0.686   0.581   0.686   0.462   0.600   0.456   0.600   0.488   0.657   0.616   0.657   0.487   0.600   0.708   0.714