IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NetMHCpan 2.8 60 60 60
NetMHCpan 3.0 65 65 65
NetMHCpan 4.0 70 70 70
SMM 85 85 85
ANN 3.4 85 85 85
ANN 4.0 40 40 40
ARB 0 0 0
SMMPMBEC 90 90 90
IEDB Consensus 85 85 85
NetMHCcons 65 65 65
PickPocket 85 85 85
mhcflurry 1.2.0 10 10 10

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 315312   HLA-A*31:01   9   10   4   binary   0.711   0.917   0.782   0.958   0.853   1.000   0.711   0.917   0.711   0.917   0.711   0.917   0.640   0.875   0.711   0.917   0.711   0.917   0.711   0.917   0.711   0.917   -   - 
 315312   HLA-A*66:01   9   16   14   binary   0.041   0.536   0.041   0.536   0.041   0.536   0.205   0.679   0.205   0.679   -0.287   0.250   -   -   0.574   1.000   0.205   0.679   0.123   0.607   0.205   0.679   -0.123   0.393