IEDB Analysis Resource

MHCI Weekly Benchmark results


Overall scores

Overall scores based on data sets submitted to the IEDB within a single week. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.

Server Overall SRCC AUC
NetMHCpan 2.8 60 60 60
NetMHCpan 3.0 72 72 72
NetMHCpan 4.0 49 49 49
SMM 9 9 9
ANN 3.4 46 46 46
ANN 4.0 100 100 100
ARB 0 0 0
SMMPMBEC 100 100 100
IEDB Consensus 27 27 27
NetMHCcons 60 60 60
PickPocket 34 33 36
mhcflurry 1.2.0 87 87 87

Data set specific results

Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here

IEDB
Reference
Allele Peptide
Length
Peptide
Count
Positive
Count
Measurement
type
NetMHCpan 2.8 NetMHCpan 3.0 NetMHCpan 4.0 SMM ANN 3.4 ANN 4.0 ARB SMMPMBEC IEDB Consensus NetMHCcons PickPocket mhcflurry 1.2.0
SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC SRCC AUC
 1029125   HLA-B*27:04   9   21   14   binary   0.717   0.939   0.801   0.990   0.801   0.990   -   -   -   -   -   -   -   -   -   -   -   -   0.717   0.939   0.534   0.827   0.734   0.949 
 1029125   HLA-B*27:05   9   21   14   binary   0.751   0.959   0.734   0.949   0.717   0.939   0.667   0.908   0.717   0.939   0.751   0.959   0.617   0.878   0.751   0.959   0.676   0.913   0.751   0.959   0.668   0.913   0.751   0.959 
 1029125   HLA-B*27:06   9   21   13   binary   0.421   0.750   0.453   0.769   0.389   0.731   -   -   -   -   -   -   -   -   -   -   -   -   0.421   0.750   0.502   0.798   0.615   0.865