MHCI Weekly Benchmark results
Overall scores
Overall scores based on data sets submitted to the IED for the last at least 3 references. The overall scores in the SRCC and AUC columns are calculated using performance values for only SRCC or AUC respectively. In the overall column, both evaluation types are used.
Server | Overall | SRCC | AUC |
---|---|---|---|
ANN 3.4 | 63 | 63 | 63 |
ANN 4.0 | 61 | 62 | 61 |
ARB | 21 | 21 | 21 |
IEDB Consensus | 39 | 38 | 39 |
NetMHCcons | 60 | 61 | 60 |
NetMHCpan 2.8 | 49 | 49 | 48 |
NetMHCpan 3.0 | 57 | 56 | 58 |
NetMHCpan 4.0 BA | 66 | 66 | 67 |
NetMHCpan 4.0 EL | 60 | 60 | 61 |
NetMHCpan 4.1 BA | 71 | 71 | 71 |
NetMHCpan 4.1 EL | 74 | 75 | 74 |
PickPocket | 35 | 35 | 35 |
SMM | 30 | 30 | 30 |
SMMPMBEC | 33 | 33 | 33 |
mhcflurry 1.2.0 | 41 | 41 | 41 |
Data set specific results
Detailed information for the evaluated data sets used in the calculation of the overall scores in the table above. Predictions from each participating server for the data sets listed below may be downloaded here
Datasets displayed in gray showed poor performance across all of the available predictors and are excluded from the overall ranking, pending further analysis.
IEDB Reference |
Allele | Peptide Length |
Peptide Count |
Positive Count |
Measurement type |
ANN 3.4 | ANN 4.0 | ARB | IEDB Consensus | NetMHCcons | NetMHCpan 2.8 | NetMHCpan 3.0 | NetMHCpan 4.0 BA | NetMHCpan 4.0 EL | NetMHCpan 4.1 BA | NetMHCpan 4.1 EL | PickPocket | SMM | SMMPMBEC | mhcflurry 1.2.0 | |||||||||||||||
SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | SRCC | AUC | ||||||
1044508 | HLA-A*01:01 | 9 | 12 | 5 | binary | 0.857 | 1.000 | 0.857 | 1.000 | 0.220 | 0.629 | 0.613 | 0.857 | 0.759 | 0.943 | 0.612 | 0.857 | 0.661 | 0.886 | 0.710 | 0.914 | 0.662 | 0.886 | 0.759 | 0.943 | 0.710 | 0.914 | 0.857 | 1.000 | 0.465 | 0.771 | 0.465 | 0.771 | 0.612 | 0.857 |
1044508 | HLA-A*03:01 | 9 | 34 | 20 | binary | 0.384 | 0.725 | 0.372 | 0.718 | 0.347 | 0.704 | 0.375 | 0.725 | 0.408 | 0.739 | 0.378 | 0.721 | 0.347 | 0.704 | 0.451 | 0.764 | 0.451 | 0.764 | 0.493 | 0.789 | 0.451 | 0.764 | 0.067 | 0.543 | 0.335 | 0.696 | 0.305 | 0.679 | 0.341 | 0.700 |
1044508 | HLA-A*03:01 | 10 | 25 | 7 | binary | 0.272 | 0.675 | 0.247 | 0.659 | 0.259 | 0.667 | 0.142 | 0.599 | 0.284 | 0.683 | 0.241 | 0.659 | 0.284 | 0.683 | 0.358 | 0.730 | 0.229 | 0.663 | 0.321 | 0.706 | 0.321 | 0.706 | 0.173 | 0.611 | 0.037 | 0.524 | 0.086 | 0.556 | 0.000 | 0.500 |
1044508 | HLA-A*11:01 | 9 | 48 | 25 | binary | 0.393 | 0.727 | 0.387 | 0.723 | 0.378 | 0.718 | 0.384 | 0.726 | 0.396 | 0.732 | 0.396 | 0.729 | 0.423 | 0.744 | 0.408 | 0.736 | 0.408 | 0.736 | 0.441 | 0.755 | 0.426 | 0.746 | 0.286 | 0.669 | 0.348 | 0.701 | 0.378 | 0.718 | 0.429 | 0.748 |
1044508 | HLA-A*11:01 | 10 | 42 | 15 | binary | -0.008 | 0.496 | -0.010 | 0.494 | 0.051 | 0.531 | 0.105 | 0.567 | -0.039 | 0.477 | -0.039 | 0.477 | -0.023 | 0.486 | -0.043 | 0.474 | 0.119 | 0.572 | 0.002 | 0.501 | 0.049 | 0.530 | -0.125 | 0.425 | 0.150 | 0.590 | 0.076 | 0.546 | 0.023 | 0.514 |
1044508 | HLA-B*07:02 | 9 | 45 | 33 | binary | 0.342 | 0.723 | 0.433 | 0.783 | 0.058 | 0.538 | 0.328 | 0.715 | 0.410 | 0.768 | 0.441 | 0.788 | 0.476 | 0.811 | 0.480 | 0.813 | 0.321 | 0.710 | 0.464 | 0.803 | 0.406 | 0.765 | 0.176 | 0.615 | 0.284 | 0.686 | 0.313 | 0.705 | 0.344 | 0.725 |
1044508 | HLA-B*07:02 | 10 | 34 | 18 | binary | 0.366 | 0.712 | 0.523 | 0.802 | 0.258 | 0.649 | 0.348 | 0.701 | 0.390 | 0.734 | 0.384 | 0.722 | 0.466 | 0.769 | 0.487 | 0.781 | 0.357 | 0.707 | 0.511 | 0.795 | 0.408 | 0.736 | 0.318 | 0.684 | 0.144 | 0.583 | 0.180 | 0.604 | 0.372 | 0.715 |
1046844 | HLA-A*02:01 | 9 | 34 | 25 | binary | 0.425 | 0.778 | 0.398 | 0.760 | -0.010 | 0.493 | 0.194 | 0.627 | 0.330 | 0.716 | 0.221 | 0.644 | 0.306 | 0.700 | 0.323 | 0.711 | 0.523 | 0.842 | 0.336 | 0.720 | 0.394 | 0.758 | 0.211 | 0.638 | 0.275 | 0.680 | 0.289 | 0.689 | 0.296 | 0.693 |
1046844 | HLA-A*02:01 | 10 | 16 | 11 | binary | 0.132 | 0.582 | 0.102 | 0.564 | -0.278 | 0.327 | -0.088 | 0.455 | 0.132 | 0.582 | 0.044 | 0.527 | 0.015 | 0.509 | 0.073 | 0.545 | 0.541 | 0.836 | 0.044 | 0.527 | 0.570 | 0.855 | -0.102 | 0.436 | -0.015 | 0.491 | -0.132 | 0.418 | 0.161 | 0.600 |
1046951 | HLA-B*07:02 | 9 | 13 | 8 | binary | 0.000 | 0.500 | 0.085 | 0.550 | 0.211 | 0.625 | 0.148 | 0.588 | 0.000 | 0.500 | 0.000 | 0.500 | 0.127 | 0.575 | 0.169 | 0.600 | -0.211 | 0.375 | 0.169 | 0.600 | -0.169 | 0.400 | 0.169 | 0.600 | 0.127 | 0.575 | 0.085 | 0.550 | 0.085 | 0.550 |
1046951 | HLA-B*13:01 | 9 | 32 | 24 | binary | - | - | - | - | - | - | - | - | 0.031 | 0.521 | 0.109 | 0.573 | 0.172 | 0.615 | 0.102 | 0.568 | -0.031 | 0.479 | 0.055 | 0.536 | 0.008 | 0.505 | -0.055 | 0.464 | - | - | - | - | - | - |
1046951 | HLA-B*13:02 | 9 | 29 | 21 | binary | - | - | - | - | - | - | - | - | 0.018 | 0.512 | 0.184 | 0.619 | 0.175 | 0.613 | 0.175 | 0.613 | -0.055 | 0.464 | 0.304 | 0.696 | 0.184 | 0.619 | 0.005 | 0.506 | - | - | - | - | - | - |
1046951 | HLA-B*15:01 | 9 | 47 | 41 | binary | 0.005 | 0.504 | 0.028 | 0.524 | 0.122 | 0.606 | 0.068 | 0.559 | 0.005 | 0.504 | 0.019 | 0.516 | 0.019 | 0.516 | 0.009 | 0.508 | -0.094 | 0.419 | 0.038 | 0.533 | 0.014 | 0.512 | 0.002 | 0.502 | 0.075 | 0.565 | 0.071 | 0.561 | -0.009 | 0.492 |
1046951 | HLA-B*15:02 | 9 | 28 | 20 | binary | 0.225 | 0.644 | 0.117 | 0.575 | 0.020 | 0.513 | 0.215 | 0.637 | 0.264 | 0.669 | 0.254 | 0.662 | 0.225 | 0.644 | 0.235 | 0.650 | 0.470 | 0.800 | 0.333 | 0.713 | 0.450 | 0.787 | 0.098 | 0.562 | 0.196 | 0.625 | 0.225 | 0.644 | 0.206 | 0.631 |
1046951 | HLA-B*35:01 | 9 | 43 | 31 | binary | 0.096 | 0.562 | 0.142 | 0.591 | 0.096 | 0.562 | 0.144 | 0.594 | 0.104 | 0.567 | 0.130 | 0.583 | 0.130 | 0.583 | 0.138 | 0.589 | 0.155 | 0.599 | 0.130 | 0.583 | 0.092 | 0.559 | 0.138 | 0.589 | 0.159 | 0.602 | 0.159 | 0.602 | 0.138 | 0.589 |
1046951 | HLA-B*40:01 | 9 | 14 | 11 | binary | 0.453 | 0.818 | 0.540 | 0.879 | 0.194 | 0.636 | 0.453 | 0.818 | 0.411 | 0.788 | 0.497 | 0.848 | 0.410 | 0.788 | 0.410 | 0.788 | 0.367 | 0.758 | 0.367 | 0.758 | 0.151 | 0.606 | 0.367 | 0.758 | 0.367 | 0.758 | 0.324 | 0.727 | 0.453 | 0.818 |
1046951 | HLA-B*46:01 | 9 | 31 | 27 | binary | -0.118 | 0.398 | -0.086 | 0.426 | -0.011 | 0.491 | -0.075 | 0.435 | -0.129 | 0.389 | -0.129 | 0.389 | -0.086 | 0.426 | -0.118 | 0.398 | -0.129 | 0.389 | -0.118 | 0.398 | -0.140 | 0.380 | -0.108 | 0.407 | -0.065 | 0.444 | -0.108 | 0.407 | -0.086 | 0.426 |
1046951 | HLA-B*51:01 | 9 | 11 | 8 | binary | 0.387 | 0.750 | 0.387 | 0.750 | 0.452 | 0.792 | -0.065 | 0.458 | 0.129 | 0.583 | 0.065 | 0.542 | 0.000 | 0.500 | 0.065 | 0.542 | 0.129 | 0.583 | 0.129 | 0.583 | 0.194 | 0.625 | 0.065 | 0.542 | 0.194 | 0.625 | 0.129 | 0.583 | 0.258 | 0.667 |
1046951 | HLA-B*58:01 | 9 | 42 | 32 | binary | 0.134 | 0.591 | 0.184 | 0.625 | 0.138 | 0.594 | 0.185 | 0.630 | 0.189 | 0.628 | 0.208 | 0.641 | 0.217 | 0.647 | 0.212 | 0.644 | 0.254 | 0.672 | 0.203 | 0.637 | 0.226 | 0.653 | 0.180 | 0.622 | 0.166 | 0.613 | 0.171 | 0.616 | 0.101 | 0.569 |
1046951 | HLA-C*01:02 | 9 | 33 | 27 | binary | - | - | - | - | - | - | - | - | 0.314 | 0.735 | 0.248 | 0.685 | 0.281 | 0.710 | 0.231 | 0.673 | 0.177 | 0.633 | 0.355 | 0.765 | 0.256 | 0.691 | 0.281 | 0.710 | - | - | - | - | - | - |
1046951 | HLA-C*03:02 | 9 | 20 | 15 | binary | - | - | - | - | - | - | - | - | 0.170 | 0.613 | 0.170 | 0.613 | 0.110 | 0.573 | 0.190 | 0.627 | 0.010 | 0.507 | 0.090 | 0.560 | -0.070 | 0.453 | 0.330 | 0.720 | - | - | - | - | - | - |
1046951 | HLA-C*03:04 | 9 | 14 | 10 | binary | - | - | - | - | - | - | - | - | 0.039 | 0.525 | 0.039 | 0.525 | 0.196 | 0.625 | 0.196 | 0.625 | 0.196 | 0.625 | 0.118 | 0.575 | 0.196 | 0.625 | 0.235 | 0.650 | - | - | - | - | - | - |
1046951 | HLA-C*04:01 | 9 | 17 | 14 | binary | - | - | 0.157 | 0.619 | - | - | 0.126 | 0.595 | -0.032 | 0.476 | -0.220 | 0.333 | -0.094 | 0.429 | -0.315 | 0.262 | -0.126 | 0.405 | -0.189 | 0.357 | 0.284 | 0.714 | -0.110 | 0.417 | 0.126 | 0.595 | 0.126 | 0.595 | -0.283 | 0.286 |
1046951 | HLA-C*06:02 | 9 | 28 | 16 | binary | -0.107 | 0.438 | -0.036 | 0.479 | - | - | -0.205 | 0.380 | -0.027 | 0.484 | 0.000 | 0.500 | 0.107 | 0.562 | 0.134 | 0.578 | 0.268 | 0.656 | - | - | 0.214 | 0.625 | 0.018 | 0.510 | - | - | -0.197 | 0.385 | 0.125 | 0.573 |
1046951 | HLA-C*07:02 | 9 | 29 | 22 | binary | 0.337 | 0.727 | 0.010 | 0.506 | - | - | 0.096 | 0.565 | 0.202 | 0.636 | 0.116 | 0.578 | 0.116 | 0.578 | 0.183 | 0.623 | 0.231 | 0.656 | 0.135 | 0.591 | 0.212 | 0.643 | 0.043 | 0.529 | 0.096 | 0.565 | 0.202 | 0.636 | 0.067 | 0.545 |
1046951 | HLA-C*08:01 | 9 | 18 | 16 | binary | - | - | - | - | - | - | - | - | -0.170 | 0.344 | -0.170 | 0.344 | -0.170 | 0.344 | -0.034 | 0.469 | -0.102 | 0.406 | -0.102 | 0.406 | 0.273 | 0.750 | -0.307 | 0.219 | - | - | - | - | - | - |
1046951 | HLA-C*14:02 | 9 | 10 | 7 | binary | 0.342 | 0.714 | 0.418 | 0.762 | - | - | 0.570 | 0.857 | 0.342 | 0.714 | 0.342 | 0.714 | 0.570 | 0.857 | 0.722 | 0.952 | 0.798 | 1.000 | 0.722 | 0.952 | 0.722 | 0.952 | 0.646 | 0.905 | 0.646 | 0.905 | 0.570 | 0.857 | 0.342 | 0.714 |